Lee County Virginia has 7 places on the National Register of Historic Places including 2 places of National significance and 2 places of Statewide significance. Significant places include Cumberland Gap Historic District, Cumberland Gap National Historical Park, Ely Mound and Jonesville Methodist Campground and Cumberland Gap National Historical Park. 
Prehistoric cultural affiliation(s) include Late Woodland and  Mississippian dating back to 500. Prominent architectural styles found in Lee Country are  Late Victorian, Bungalow/Craftsman and  Federal.